Olabisi Lab


Stable Cell line
Mouse model
iPSC-based models
Using several cellular models and APOL1-transgenic mouse models, we investigate questions including:
  • What upstream mechanisms regulate APOL1 expression?
  • What downstream mechanisms mediate APOL1 function?
  • Which proteins interact with APOL1 protein?
  • Which cellular processes are regulated or dysregulated by APOL1?
  • How do variants APOL1 cause injury to kidney cells ?